Neurology Updates

Neurology Updates

Here you will find regular scientific news from our Scientific Panels. We cover all areas of neurology, including rare diseases. The most recent news are displayed below. You will find all news of different areas sorted into the subsections of the respective scientific panel. Enjoy reading!

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| Dementia and cognitive disorders  

Blood phosphorylated tau 181 as a biomarker for Alzheimer’s disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts

Blood p-tau 181 is sensitive for identifying clinically diagnosed AD patients in the very early disease stages; differentiates AD from other…

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Created by Svetlana Tomic1,2, Zvonimir Popovic1,2, Francesco Di Lorenzo3,4

| Dementia and cognitive disorders  

Longitudinal neuroimaging biomarkers differ across Alzheimer’s disease phenotypes

Each AD phenotype had its own pattern of baseline and rates of change in tau pathology and grey matter loss, with some overlap particularly in the…

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Created by Svetlana Tomic1,2, Zvonimir Popovic1,2, Francesco Di Lorenzo3,4

| Coma & Chronic Disorders of Consciousness  

Auditory localisation could be considered as a new sign of the minimally conscious state

Auditory localization should be considered as a sign of consciousness, as unresponsive patients who demonstrate this behaviour show increased brain…

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Created by Manon Carrière, Coma Science Group, University of Liège and Centre du Cerveau2, University Hospital of Liège; Edited by Dr Leandro R. D. Sanz (SP Management Group)

| Coma & Chronic Disorders of Consciousness  

Discontinuation of artificial nutrition and hydration and covert cognition

The process of end-of-life decision-making for patients with disorders of consciousness should include caregivers in bedside assessments and integrate…

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Created by Rita Formisano, IRCCS, Santa Lucia Foundation, Rome; Edited by Dr Leandro R. D. Sanz (SP Management Group)

| Coma & Chronic Disorders of Consciousness  

Multi-center prospective study on predictors of short-term outcome in disorders of consciousness

An international study showed that younger age, shorter time since injury, higher level of responsiveness and EEG reactivity to eye opening are all…

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Created by Anna Estraneo, IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy; Neurology Unit, SM della Pietà General Hospital, Nola, Italy; Edited by Dr Leandro R. D. Sanz (SP Management Group)

| Coma & Chronic Disorders of Consciousness  

Habituation to auditory startle as a new sign of the minimally conscious state, and neurophysiological evidence for cortical effects of transcranial electric stimulation

Habituation of auditory startle reflex should be considered as a sign of the minimally conscious state, as unresponsive patients who demonstrate this…

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Created by Benjamin Rohaut, Sorbonne University and Pitié-Salpêtrière Hospital, Paris, France; Edited by Dr Leandro R. D. Sanz (SP Management Group)

| Coma & Chronic Disorders of Consciousness  

Short and long-term outcomes of early intensive neurorehabilitation for disorders of consciousness: a prospective cohort study

A Dutch nationwide prospective cohort study has been launched to monitor the outcomes of patients included in the Early Intensive Rehabilitation…

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Created by Danielle Driessen Radboud UMC, The Netherlands, Edited by Dr Leandro R. D. Sanz (SP Management Group)

| Coma & Chronic Disorders of Consciousness  

Transcutaneous auricular vagal nerve stimulation and disorders of consciousness: a hypothesis for mechanisms of action

The Vagal Cortical Pathways model aims to explain possible mechanisms for the action of transcutaneous auricular vagal nerve stimulation to promote…

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Created by Marie-Michele Briand 1, 2, 3

| Palliative Care  

The effects of the COVID 19 pandemic on the palliative care for neurological patients

The COVID 19 pandemic has affected people with neurological disease and reduced the care provided, with possible adverse sequelae, including frailty.

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Created by Professor David Oliver, University of Kent

| Palliative Care  

Palliative care for neurological patients

A new study has shown that a short-term palliative care intervention was seen positively by the patients and families and reduced costs, but did not…

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Created by Professor David Oliver, University of Kent

| Autonomic nervous system disorders  

Autonomic nervous system abnormalities predict cardiovascular changes after initiation of siponimod in secondary progressive multiple sclerosis

Siponimod has been associated with decrease in HR at treatment initiation and development of hypertension during treatment, which may be predicted by…

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Created by Dr. Alessandra Fanciulli, MD, PhD

| Pain  

Managing pain during the COVID-19 pandemic

Pain management, covid-19 pandemic, recommendations

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Created by 1Nina Vashchenko; 2Katarina Ivana Tudor