Knowledge Distillery

In this case series, the authors systematically assessed the presence of deep vein thrombosis among patients with severe COVID-19 in an intensive care…

Genomic evidence for reinfection with SARS-CoV-2: a case study

In this paper, recently published in Lancet, the authors report the findings of autopsies of six patients (four men and two women, aged 58–82 years)…

A novel variant of concern (VOC) named CAL.20C (B.1.427/B.1.429), originally detected in California, carries spike glycoprotein mutations S13I in the…

Remdesivir for the Treatment of Covid-19 — Final Report

In this open-label, multicentre, randomised clinical trial, recently published in JAMA, the authors evaluate the efficacy and adverse effects of…

In this article the authors combine cryo-EM, binding and computational analyses to study variant spikes, including one that was involved in…

Efficacy of Tocilizumab in Patients Hospitalized with COVID-19

This review, recently published in JAMA Neurology, serves to summarise available information regarding coronaviruses in the nervous system, identifies…

In this article the authors report cryo-EM structures of the full-length spike (S) trimers of the B.1.1.7 and B.1.351 variants, as well as their…

Effect of Tocilizumab vs Usual Care in Adults Hospitalized With COVID-19 and Moderate or Severe Pneumonia A Randomized Clinical Trial

One of the immediate and ongoing neurological challenges posed by the COVID-19 pandemic is the management of patients who are undergoing immunotherapy…