Knowledge Distillery

In this study the authors did a multicentric, open-label, Bayesian randomised, adaptive, phase 2/3 clinical trial, nested within the CORIMUNO-19…

Development and validation of a risk score using complete blood count to predict in-hospital mortality in COVID-19 Patients

In this paper, the authors report a case of a previously healthy 58-year-old man who acutely developed hyposmia, generalised myoclonus, fluctuating…

Diverse Functional Autoantibodies in Patients with COVID-19

Adults in receipt of a single dose of ChAdOx1 or BNT162b2 were enrolled at 12 UK sites and randomly assigned to receive concomitant administration of…

Adaptive immunity to SARS-CoV-2 and COVID-19

In this review recently published in JAMA, the authors summarise the current evidence regarding the pathophysiology, transmission, diagnosis, and…

3-month, 6-month, 9-month, and 12-month respiratory outcomes in patients following COVID-19-related hospitalisation: a prospective study

In this trial, done at 43 centres in France, the authors randomly assigned patients receiving invasive mechanical ventilation for up to 72 h with…

MDA5 governs the innate immune response to SARS-CoV-2 in lung epithelial cells

In this multicentre retrospective observational study, the authors analysed the impact of the COVID-19 pandemic on hospital stroke admissions and…

Impact and effectiveness of mRNA BNT162b2 vaccine against SARS-CoV-2 infections and COVID-19 cases, hospitalisations, and deaths following a…