Knowledge Distillery

Genetic variants of SARS-CoV-2—what do they mean?

In this paper, the authors pooled all consecutive patients hospitalised with laboratory-confirmed COVID-19 and acute ischaemic stroke across 28 sites…

Face masks effectively limit the probability of SARS-CoV-2 transmission

In this study the authors did a multicentric, open-label, Bayesian randomised, adaptive, phase 2/3 clinical trial, nested within the CORIMUNO-19…

Development and validation of a risk score using complete blood count to predict in-hospital mortality in COVID-19 Patients

In this paper, the authors report a case of a previously healthy 58-year-old man who acutely developed hyposmia, generalised myoclonus, fluctuating…

Diverse Functional Autoantibodies in Patients with COVID-19

Adults in receipt of a single dose of ChAdOx1 or BNT162b2 were enrolled at 12 UK sites and randomly assigned to receive concomitant administration of…

Adaptive immunity to SARS-CoV-2 and COVID-19

In this review recently published in JAMA, the authors summarise the current evidence regarding the pathophysiology, transmission, diagnosis, and…

3-month, 6-month, 9-month, and 12-month respiratory outcomes in patients following COVID-19-related hospitalisation: a prospective study

In this trial, done at 43 centres in France, the authors randomly assigned patients receiving invasive mechanical ventilation for up to 72 h with…