Neurology Updates

Neurology Updates

Here you will find regular scientific news from our Scientific Panels. We cover all areas of neurology, including rare diseases. The most recent news are displayed below. You will find all news of different areas sorted into the subsections of the respective scientific panel. Enjoy reading!

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| ALS and frontotemporal dementia | Rare Neurological Diseases  

Hippocampal aggregation signatures of pathogenic UBQLN2 in amyotrophic lateral sclerosis and frontotemporal dementia

The central pathological hallmark of ALS is the presence of cytoplasmic inclusions or aggregates in degenerating motor neurons and surrounding…

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Created by Mariam Kekenadze

| ALS and frontotemporal dementia | Rare Neurological Diseases  

Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD

Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) show similarities in pathology and genetics, hinting at shared…

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Created by Alessandro Bombaci

| ALS and frontotemporal dementia | Rare Neurological Diseases  

Novel approaches to motoneuron disease/ALS treatment using non-invasive brain and spinal stimulation: IFCN handbook chapter.

This article provides a comprehensive review of the studies using non-invasive brain and spinal stimulation in motor neuron disease, with a focus on…

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Created by Dubbioso Raffaele

| ALS and frontotemporal dementia | Rare Neurological Diseases  

Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD

This study provides further insights in the consequences of mislocalization of the protein TDP-43 from the nucleus to the cytoplasm which is a…

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Created by Prof. Susanne Petri

| COVID-19 | ALS and frontotemporal dementia  

Amyotrophic Lateral Sclerosis and COVID-19 – Recommendations to patients and caregivers

In patients with Amyotrophic Lateral Sclerosis (ALS), the impact of respiratory infections is expected to be more serious than in the general…

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Created by Susana Pinto

| ALS and frontotemporal dementia | Rare Neurological Diseases  

Amyotrophic Lateral Sclerosis

It was l suggested a long time ago, that ALS is rather a cortical than a spinal disease. The work of Heiko Braak and collaborators has demonstrated…

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Created by Prof. Andrew Eisen, Vancouver

| ALS and frontotemporal dementia  

Safety and efficacy of diaphragm pacing in patients with respiratory insufficiency due to amyotrophic lateral sclerosis (DiPALS): a multicentre, open-label, randomised controlled trial.

In this work the therapeutic value of a diaphragm pacemaker  is examined on a trial in patients with amyothropic lateral sclerosis. Patients underwent…

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Created by Albert Ludolph

| ALS and frontotemporal dementia  

A revision of the El Escorial criteria – 2015.

The current diagnostic criteria for ALS, the El Escorial Criteria, have met with criticism by the community (Agosta F, Al-Chalabi A, Filippi M, Hardim…

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Created by Albert Ludolph