Knowledge Distillery

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| Case series/case reports  

The prolonged mechanical ventilation that is often required by patients with severe COVID-19 is expected to result in significant intensive care…

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| Interventional study with open label/non-randomised methodology  

BNT162b2 is a lipid nanoparticle–formulated, nucleoside-modified RNA vaccine encoding a prefusion-stabilized, membrane-anchored severe acute…

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| Randomised double-blinded placebo-controlled trial  

LY-CoV555, a neutralising monoclonal antibody, has been associated with a decrease in viral load and frequency of hospitalisations or emergency…

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| Randomised double-blinded placebo-controlled trial  

Recent data suggest that complications and death from COVID-19 may be related to high viral loads.

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| Randomised double-blinded placebo-controlled trial  

The efficacy of interleukin-6 receptor blockade in hospitalised patients with COVID-19 who are not receiving mechanical ventilation is unclear.

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| Randomised double-blinded placebo-controlled trial  

Severe COVID-19 is associated with dysregulated inflammation. The effects of combination treatment with baricitinib, a Janus kinase inhibitor, plus…

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| Randomised double-blinded placebo-controlled trial  

NVX-CoV2373 is a recombinant severe acute respiratory syndrome coronavirus 2 (rSARS-CoV-2) nanoparticle vaccine composed of trimeric full-length…

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| Cross-sectional case-control studies  

Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) have been postulated to affect susceptibility to COVID-19.…

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| Observational study: prospective longitudinal cohort  

In this paper, recently published in the Journal of Neurology, Neurosurgery and Psychiatry, the authors report initial findings of an ongoing…

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| Observational study: prospective longitudinal cohort  

In this longitudinal study, recently published in the European Journal of Neurology, the authors sought to describe the neurological manifestations of…

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| Case series/case reports  

In this paper, recently published in Neurocritical Care, the authors conducted a retrospective cohort study of patients with haemorrhagic stroke (both…

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| Case series/case reports  

In this paper, recently published in Stroke, the authors aimed to compare anterior circulation large vessel occlusion stroke severity between patients…

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