Knowledge Distillery

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| Observational study: prospective longitudinal cohort  

Interim results from a phase 3 trial of the Moderna mRNA-1273 SARS-CoV-2 vaccine indicated 94% efficacy in preventing COVID-19.

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| Observational study: prospective longitudinal cohort  

Since the start of the vaccination campaign, the development of COVID-19 has been reported in persons who have received one or both doses of mRNA-1273…

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| Observational study: prospective longitudinal cohort  
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| Randomised double-blinded placebo-controlled trial  

CoV2 preS dTM is a stabilised pre-fusion spike protein vaccine produced in a baculovirus expression system being developed against SARS-CoV-2.

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| Randomised double-blinded placebo-controlled trial  

In this phase 1, double-blind, placebo-controlled, block-randomised trial the authors aimed to assess the safety and immunogenicity of an…

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| Meta-analysis Systematic Review  

The comparative performance of different clinical sampling methods for diagnosis of SARS-CoV-2 infection by RT-PCR among populations with suspected…

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| Randomised double-blinded placebo-controlled trial  

A new variant of SARS-CoV-2, B.1.1.7, emerged as the dominant cause of COVID-19 disease in the UK from November, 2020.

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| Randomised double-blinded placebo-controlled trial  

Data on the efficacy of hydroxychloroquine or lopinavir-ritonavir for the treatment of high-risk outpatients with COVID-19 in developing countries are…

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| Case series/case reports  

Acute ischemic stroke (AIS) is a known neurological complication in patients with respiratory symptoms of COVID-19 infection.

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| Randomised double-blinded placebo-controlled trial  

High-flow nasal oxygen is recommended as initial treatment for acute hypoxemic respiratory failure and is widely applied in patients with COVID-19.

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| Observational study: prospective longitudinal cohort  

The acute clinical manifestations of COVID-19 are well characterized; however, its post-acute sequalae have not been comprehensively described.

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