Knowledge Distillery

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| Observational study: prospective longitudinal cohort  

This prospective cohort study enrolled 8 hospitalized COVID-19 patients and assessed them at subacute and chronic stage (after 6 months) with MoCA and…

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| Miscellaneous  

This retrospective cohort study used the TriNetX electronic health records network, which has over 81 million patients’ data, to estimate the…

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| Observational study: prospective longitudinal cohort  

Evidence is urgently needed to support treatment decisions for children with multisystem inflammatory syndrome (MIS-C) associated with severe acute…

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| Observational study: prospective longitudinal cohort  

The assessment of real-world effectiveness of immunomodulatory medications for multisystem inflammatory syndrome in children (MIS-C) may guide…

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| Randomised double-blinded placebo-controlled trial  

The efficacy and safety of tofacitinib, a Janus kinase inhibitor, in patients who are hospitalized with coronavirus disease 2019 (COVID-19) pneumonia…

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| Randomised double-blinded placebo-controlled trial  

The major complication of COVID-19 is hypoxaemic respiratory failure from capillary leak and alveolar oedema. Experimental and early clinical data…

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| Interventional study with open label/non-randomised methodology  

SARS-CoV-2 entry in human cells depends on angiotensin-converting enzyme 2, which can be upregulated by inhibitors of the renin–angiotensin system…

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| Interventional study with open label/non-randomised methodology  

COVID-19 is associated with a prothrombotic state leading to adverse clinical outcomes. Whether therapeutic anticoagulation improves outcomes in…

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| Observational study: prospective longitudinal cohort  

Adolescence represents a crucial developmental period in shaping mental health trajectories. In this longitudinal, population-based study the authors…

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| Case series/case reports  

Two mRNA vaccines, BNT162b2 (Pfizer-BioNTech) and mRNA-1273 (Moderna), received Emergency Use Authorization from the US Food and Drug Administration.…

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| Cross-sectional case-control studies  

Venous thromboembolism (VTE) is a common complication of COVID-19. It is not well understood how hospitals have managed VTE prevention and the effect…

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| Cross-sectional case-control studies  

Myalgia, increased levels of creatine kinase, and persistent muscle weakness have been reported in patients with COVID-19. The objective of this…

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