Knowledge Distillery

CoV2 preS dTM is a stabilised pre-fusion spike protein vaccine produced in a baculovirus expression system being developed against SARS-CoV-2. In this…

The Ad26.COV2.S vaccine is a recombinant, replication-incompetent human adenovirus type 26 vector encoding full-length SARS-CoV-2 spike protein in a…

This randomized, double-blind, placebo-controlled phase 3 trial was conducted at 39 hospitals in Europe and the United States.

The objective of this randomized clinical trial was to determine whether oral azithromycin in outpatients with SARS-CoV-2 infection leads to absence…

In this trial, the authors assigned COVID-19 patients to receive either one unit of convalescent plasma with a high titer of antibodies against severe…

This study randomly assigned participants who were enrolled within 96 hours after a household contact received a diagnosis of SARS-CoV-2 infection to…

This study evaluates the efficacy and safety of baricitinib in combination with standard of care for the treatment of hospitalised adults with…

The objective of this study was to assess whether anticoagulant or antiplatelet therapy can safely reduce major adverse cardiopulmonary outcomes among…

This trial tested the safety and efficacy of levosimendan in improving supine slow vital capacity after 12 weeks of treatment in 496 people with…

Safe, effective vaccines against coronavirus disease 2019 (COVID-19) are urgently needed in children younger than 12 years of age. In this article the…

Adults in receipt of a single dose of ChAdOx1 or BNT162b2 were enrolled at 12 UK sites and randomly assigned to receive concomitant administration of…

In this trial, done at 43 centres in France, the authors randomly assigned patients receiving invasive mechanical ventilation for up to 72 h with…