Knowledge Distillery

The authors investigated the safety, vaccine efficacy, and immunogenicity of two doses of AZD1222 as compared with placebo in preventing the onset of…

Evaluation of the effects of therapeutic-dose low-molecular-weight heparin vs institutional standard prophylactic or intermediate-dose heparins for…

The objective of this study was to determine whether convalescent plasma would improve outcomes for critically ill adults with COVID-19.

In this randomised, controlled, open-label, platform trial, several possible treatments were compared with usual care in patients hospitalised with…

In this article the authors aimed to report the results of a substudy within a phase 3 UK trial, by evaluating the safety, immunogenicity, and…

In this study the authors did a multicentric, open-label, Bayesian randomised, adaptive, phase 2/3 clinical trial, nested within the CORIMUNO-19…

Our highlighted selection of Covid-related interventional studies with open label or non-randomised methodology from the scientific press for January…

Our highlighted selection of Covid-related interventional studies with open label or non-randomised methodology from the scientific press for February…

Multiple early reports of patients admitted to hospital with COVID-19 showed that patients with chronic respiratory disease were significantly…

Many patients with COVID-19 have been treated with plasma containing anti-SARS-CoV-2 antibodies

BNT162b2 is a lipid nanoparticle–formulated, nucleoside-modified RNA vaccine encoding a prefusion-stabilized, membrane-anchored severe acute…

SARS-CoV-2 entry in human cells depends on angiotensin-converting enzyme 2, which can be upregulated by inhibitors of the renin–angiotensin system…