| Neuro-ophthalmology and -otology  

The Semont-Plus is superior to the regular Semont and Epley maneuvers for the treatment of posterior canal benign paroxysmal positional vertigo

In two randomized prospective trials the time until recovery in posterior canal BPPV was significantly reduced by the Semont-Plus maneuver in comparison to the regular Semont maneuver and the Epley maneuver.

Benign paroxysmal positioning vertigo (BPPV) is the most frequent peripheral vestibular disorder. Most often the posterior canal is affected: pcBPPV. For its treatment, there is Level 1 evidence that the Semont maneuver (SM) and the Epley maneuver (EM) are effective. However, a meta-analysis concluded that many patients suffer longer and are more impaired than previously assumed. A biophysical model and computer simulations showed that during the rotation of the labyrinth the crystals move about 25° less than the rotation of the canal [1]. Based on these findings, the Semont-Plus (SM+) was developed: the patient’s body is moved towards the affected side 60°+ below earth horizontal. In this way, the otoconia move 60°+ further in the direction of the utricle, which should theoretically increase the effectivity. In two prospective randomized tri-national studies, it was demonstrated that the SM+ is superior to (A) the regular SM: in the 194 patients analyzed, it took 2 days (median, mean: 3.6 days) for recovery with SM and 1 day (median, mean: 1.8 days) with SM+ (p=.001, 2-sided Mann-Whitney-U-test [2]; and

(B) the EM: in the 195 patients analyzed, it took 1 day (median, mean: 1.96 days) in the SM+ group and 2 days (median, mean: 3.34 days, p=.012) in the EM group [3].

Based on these three studies, the SM+ maneuver can be recommended for the treatment pcBPPV in clinical practice.

Key Points:

  • For the treatment of the common condition posterior canal BPPV (pcBPPV) canalolithiasis, it was shown that the Semont maneuver (SM) and the Epley maneuver (EM) are effective.
  • In a biophysical model and computer simulations, it was demonstrated that during the rotation of the labyrinth the crystals move about 25° less than the rotation of the canal, i.e. they are not beyond the vertex of the canal when the patient moves towards the non-affected side.
  • The new Semont-Plus maneuver (SM+) overcomes this limitation because the patient is moved 60°+ below earth horizontal so that the otoconia are beyond the vertex of the canal.
  • Two randomized multinational prospective trials showed that the time until recovery is significantly reduced by SM+ in comparison to the regular SM and the EM; therefore the SM+ can be recommended for your clinical practice

References:

  1. Obrist D, Nienhaus A, Zamaro E, Kalla R, Mantokoudis G, Strupp M (2016) Determinants for a Successful Semont Maneuver: An In vitro Study with a Semicircular Canal Model. Front Neurol 7:150
  2. Strupp M, Goldschagg N, Vinck AS, Bayer O, Vandenbroeck S, Salerni L, Hennig A, Obrist D, Mandala M (2021) BPPV: Comparison of the SemontPLUS With the Semont Maneuver: A Prospective Randomized Trial. Front Neurol 12:652573
  3. Strupp M, Mandala  M, Vinck AS, van Breda L, Salerni L, Gerb J, Bayer O, Mavrodiev V, Goldschagg N (2023) The Semont-plus maneuver or the Epley maneuver in posterior canal BPPV: a randomized prospective study. JAMA Neurology (in press)

Publish on behalf of the Scientific Panel on Neuro-ophthalmology and -otology