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SARS-CoV-2 antibody testing for estimating COVID-19 prevalence in the population

SARS-CoV-2 antibody testing for estimating COVID-19 prevalence in the population

 

Reliable antibody testing against SARS-CoV-2 has the potential to uncover population-wide spread of COVID-19, which is critical for making informed healthcare and economic decisions. In this article, the authors review different types of antibody tests available for SARS-CoV-2 and their application for population scale testing. Biases due to varying test accuracy, results of ongoing large-scale serological studies, and the use of antibody testing for monitoring the development of “herd immunity” are summarised. The authors underlined that, while current SARS-CoV-2 antibody testing efforts have generated valuable insights, the accuracy of serological tests and selection criteria of tested cohorts need to be carefully evaluated.

DOI: https://doi.org/10.1016/j.xcrm.2021.100191